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Transforming growth factor-β pathway activity in glioblastoma

Transforming growth factor (TGF)-β is a central molecule maintaining the malignant phenotype of glioblastoma. Anti-TGF-β strategies are currently being explored in early clinical trials. Yet, there is little contemporary data on the differential expression of TGF-β isoforms at the mRNA and protein l...

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Detalles Bibliográficos
Autores principales: Frei, Karl, Gramatzki, Dorothee, Tritschler, Isabel, Schroeder, Judith Johanna, Espinoza, Larisa, Rushing, Elisabeth Jane, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467414/
https://www.ncbi.nlm.nih.gov/pubmed/25849941