Context influences on TALE–DNA binding revealed by quantitative profiling

Transcription activator-like effector (TALE) proteins recognize DNA using a seemingly simple DNA-binding code, which makes them attractive for use in genome engineering technologies that require precise targeting. Although this code is used successfully to design TALEs to target specific sequences,...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogers, Julia M., Barrera, Luis A., Reyon, Deepak, Sander, Jeffry D., Kellis, Manolis, Joung, J Keith, Bulyk, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467457/
https://www.ncbi.nlm.nih.gov/pubmed/26067805
http://dx.doi.org/10.1038/ncomms8440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467457/
https://www.ncbi.nlm.nih.gov/pubmed/26067805
http://dx.doi.org/10.1038/ncomms8440

Ejemplares similares