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Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

The opportunistic intracellular pathogen Legionella pneumophila is the causative agent of Legionnaires’ disease. L. pneumophila delivers nearly 300 effector proteins into host cells for the establishment of a replication-permissive compartment known as the Legionella-containing vacuole (LCV). SidC a...

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Detalles Bibliográficos
Autores principales: Luo, Xi, Wasilko, David J., Liu, Yao, Sun, Jiayi, Wu, Xiaochun, Luo, Zhao-Qing, Mao, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467491/
https://www.ncbi.nlm.nih.gov/pubmed/26067986
http://dx.doi.org/10.1371/journal.ppat.1004965