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Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation

BACKGROUND: In cancer cells in vitro, the glycolytic pathway and the mitochondrial tricarboxylic acid (TCA) cycle are programmed to produce more precursor molecules, and relatively less ATP, than in differentiated cells. We address the questions of whether and where these changes occur in vivo in gl...

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Detalles Bibliográficos
Autores principales: Grillon, Emmanuelle, Farion, Régine, Reuveni, Moshe, Glidle, Andrew, Rémy, Chantal, Coles, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467611/
https://www.ncbi.nlm.nih.gov/pubmed/26032618
http://dx.doi.org/10.1186/s13104-015-1191-z