The effects of phosphodiesterase-5 inhibitor sildenafil against post-resuscitation myocardial and intestinal microcirculatory dysfunction by attenuating apoptosis and regulating microRNAs expression: essential role of nitric oxide syntheses signaling

BACKGROUND: Recent experimental and clinical studies have indicated the cardioprotective role of sildenafil during ischemia/reperfusion (I/R) injury. Sildenafil has been shown to attenuate postresuscitation myocardial dysfunction in piget models of ventricular fibrillation. This study was designed t...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Wang, Guoxing, Yuan, Wei, Wu, Junyuan, Wang, Miaomiao, Li, ChunSheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467614/
https://www.ncbi.nlm.nih.gov/pubmed/26040988
http://dx.doi.org/10.1186/s12967-015-0550-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467614/
https://www.ncbi.nlm.nih.gov/pubmed/26040988
http://dx.doi.org/10.1186/s12967-015-0550-9

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