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Anti-dsDNA antibodies induce inflammation via endoplasmic reticulum stress in human mesangial cells
BACKGROUND: Anti-dsDNA antibodies play an important role in the pathogenesis of lupus nephritis (LN). Endoplasmic reticulum (ER) stress is a physical reaction under stressful condition and can cause inflammation when stimulation is sustained. This study investigated the roles of ER stress in anti-ds...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467615/ https://www.ncbi.nlm.nih.gov/pubmed/26040555 http://dx.doi.org/10.1186/s12967-015-0536-7 |