Anti-dsDNA antibodies induce inflammation via endoplasmic reticulum stress in human mesangial cells

BACKGROUND: Anti-dsDNA antibodies play an important role in the pathogenesis of lupus nephritis (LN). Endoplasmic reticulum (ER) stress is a physical reaction under stressful condition and can cause inflammation when stimulation is sustained. This study investigated the roles of ER stress in anti-ds...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Zhao, Chunmei, Wang, Shuang, Huang, Yuefang, Wang, Hongyue, Zhao, Jijun, Yang, Niansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467615/
https://www.ncbi.nlm.nih.gov/pubmed/26040555
http://dx.doi.org/10.1186/s12967-015-0536-7

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