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The effect of ataxia-telangiectasia mutated kinase-dependent hyperphosphorylation of checkpoint kinase-2 on oligodeoxynucleotide 7909 containing CpG motifs-enhanced sensitivity to X-rays in human lung adenocarcinoma A549 cells

OBJECTIVE: The aim of the study reported here was to further investigate the potential effect of ataxia-telangiectasia mutated (ATM) kinase-dependent hyperphosphorylation of checkpoint kinase-2 (Chk2) on radiosensitivity enhanced by oligodeoxynucleotide 7909 containing CpG motifs (CpG ODN7909) in hu...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoqun, Liu, Xiangdong, Qiao, Tiankui, Chen, Wei, Yuan, Sujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467653/
https://www.ncbi.nlm.nih.gov/pubmed/26089688
http://dx.doi.org/10.2147/OTT.S80288