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Cissus quadrangularis inhibits IL-1β induced inflammatory responses on chondrocytes and alleviates bone deterioration in osteotomized rats via p38 MAPK signaling

INTRODUCTION: Inflammatory mediators are key players in the pathogenesis of osteoarthritis (OA) and bone destruction. Conventional drugs suppress symptomatic activity and have no therapeutic influence on disease. Cissus quadrangularis and Withania somnifera are widely used for the treatment of bone...

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Detalles Bibliográficos
Autores principales: Kanwar, Jagat R, Samarasinghe, Rasika M, Kumar, Kuldeep, Arya, Ramesh, Sharma, Sanjeev, Zhou, Shu-Feng, Sasidharan, Sreenivasan, Kanwar, Rupinder K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467655/
https://www.ncbi.nlm.nih.gov/pubmed/26089642
http://dx.doi.org/10.2147/DDDT.S77369