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Dexmedetomidine ameliorates acute lung injury following orthotopic autologous liver transplantation in rats probably by inhibiting Toll-like receptor 4–nuclear factor kappa B signaling

BACKGROUND: To investigate whether pretreatment with dexmedetomidine (Dex) has a protective effect against acute lung injury (ALI) in an orthotopic autologous liver transplantation (OALT) rat model and to explore the mechanisms responsible for the protective effect of Dex against lung injury. METHOD...

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Detalles Bibliográficos
Autores principales: Chi, Xinjin, Wei, Xiaoxia, Gao, Wanling, Guan, Jianqiang, Yu, Xiaofan, Wang, Yiheng, Li, Xi, Cai, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467671/
https://www.ncbi.nlm.nih.gov/pubmed/26070954
http://dx.doi.org/10.1186/s12967-015-0554-5