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Validation of an Ion Torrent Sequencing Platform for the Detection of Gene Mutations in Biopsy Specimens from Patients with Non-Small-Cell Lung Cancer

BACKGROUND: Treatment for patients with advanced non-small cell lung cancer (NSCLC) is often determined by the presence of biomarkers that predict the response to agents targeting specific molecular pathways. Demands for multiplex analysis of the genes involved in the pathogenesis of NSCLC are incre...

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Detalles Bibliográficos
Autores principales: Fujita, Shiro, Masago, Katsuhiro, Takeshita, Jumpei, Okuda, Chiyuki, Otsuka, Kyoko, Hata, Akito, Kaji, Reiko, Katakami, Nobuyuki, Hirata, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467975/
https://www.ncbi.nlm.nih.gov/pubmed/26076009
http://dx.doi.org/10.1371/journal.pone.0130219