A Randomized Controlled Trial on the Effect of Tapentadol and Morphine on Conditioned Pain Modulation in Healthy Volunteers

BACKGROUND: Modulatory descending pathways, originating at supraspinal sites that converge at dorsal horn neurons, influence pain perception in humans. Defects in descending pain control are linked to chronic pain states and its restoration may be a valuable analgesic tool. Conditioned pain modulati...

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Detalles Bibliográficos
Autores principales: Martini, Chris, van Velzen, Monique, Drewes, Asbjørn, Aarts, Leon, Dahan, Albert, Niesters, Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467981/
https://www.ncbi.nlm.nih.gov/pubmed/26076171
http://dx.doi.org/10.1371/journal.pone.0128997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467981/
https://www.ncbi.nlm.nih.gov/pubmed/26076171
http://dx.doi.org/10.1371/journal.pone.0128997

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