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A Randomized Controlled Trial on the Effect of Tapentadol and Morphine on Conditioned Pain Modulation in Healthy Volunteers
BACKGROUND: Modulatory descending pathways, originating at supraspinal sites that converge at dorsal horn neurons, influence pain perception in humans. Defects in descending pain control are linked to chronic pain states and its restoration may be a valuable analgesic tool. Conditioned pain modulati...
Autores principales: | Martini, Chris, van Velzen, Monique, Drewes, Asbjørn, Aarts, Leon, Dahan, Albert, Niesters, Marieke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467981/ https://www.ncbi.nlm.nih.gov/pubmed/26076171 http://dx.doi.org/10.1371/journal.pone.0128997 |
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