Combination Treatment with All-Trans Retinoic Acid Prevents Cisplatin-Induced Enrichment of CD133(+) Tumor-Initiating Cells and Reveals Heterogeneity of Cancer Stem Cell Compartment in Lung Cancer

The existence of specific cellular subpopulations within primary tumors with increased tumorigenic potential and chemotherapy resistance (tumor-initiating cells, TICs) holds great therapeutic implications. Resistant cells can remain quiescent for long periods and be responsible for local relapses an...

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Detalles Bibliográficos
Autores principales: Moro, Massimo, Bertolini, Giulia, Pastorino, Ugo, Roz, Luca, Sozzi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467987/
https://www.ncbi.nlm.nih.gov/pubmed/26020124
http://dx.doi.org/10.1097/JTO.0000000000000563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467987/
https://www.ncbi.nlm.nih.gov/pubmed/26020124
http://dx.doi.org/10.1097/JTO.0000000000000563

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