The landscape and therapeutic relevance of cancer-associated transcript fusions

Transcript fusions as a result of chromosomal rearrangements have been a focus of attention in cancer as they provide attractive therapeutic targets. To identify novel fusion transcripts with the potential to be exploited therapeutically, we analyzed RNA sequencing, DNA copy number and gene mutation...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshihara, Kosuke, Wang, Qianghu, Torres-Garcia, Wandaliz, Zheng, Siyuan, Vegesna, Rahulsimham, Kim, Hoon, Verhaak, Roel GW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468049/
https://www.ncbi.nlm.nih.gov/pubmed/25500544
http://dx.doi.org/10.1038/onc.2014.406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468049/
https://www.ncbi.nlm.nih.gov/pubmed/25500544
http://dx.doi.org/10.1038/onc.2014.406

Ejemplares similares