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The landscape and therapeutic relevance of cancer-associated transcript fusions
Transcript fusions as a result of chromosomal rearrangements have been a focus of attention in cancer as they provide attractive therapeutic targets. To identify novel fusion transcripts with the potential to be exploited therapeutically, we analyzed RNA sequencing, DNA copy number and gene mutation...
Autores principales: | Yoshihara, Kosuke, Wang, Qianghu, Torres-Garcia, Wandaliz, Zheng, Siyuan, Vegesna, Rahulsimham, Kim, Hoon, Verhaak, Roel GW |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468049/ https://www.ncbi.nlm.nih.gov/pubmed/25500544 http://dx.doi.org/10.1038/onc.2014.406 |
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