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Evaluation of Borrelia burgdorferi BbHtrA Protease as a Vaccine Candidate for Lyme Borreliosis in Mice

Borrelia burgdorferi synthesizes an HtrA protease (BbHtrA) which is a surface-exposed, conserved protein within Lyme disease spirochetes with activity toward CheX and BmpD of Borrelia spp, as well as aggrecan, fibronectin and proteoglycans found in skin, joints and neural tissues of vertebrates. An...

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Detalles Bibliográficos
Autores principales: Ullmann, Amy J., Russell, Theresa M., Dolan, Marc C., Williams, Martin, Hojgaard, Andrias, Weiner, Zachary P., Johnson, Barbara J. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468080/
https://www.ncbi.nlm.nih.gov/pubmed/26076465
http://dx.doi.org/10.1371/journal.pone.0128868