Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent

Female 129:Stat1-null mice (129S6/SvEvTac-Stat1(tm1Rds) homozygous) uniquely develop estrogen-receptor (ER)-positive mammary tumors. Herein we report that the mammary glands (MG) of these mice have altered growth and development with abnormal terminal end buds alongside defective branching morphogen...

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Detalles Bibliográficos
Autores principales: Chen, Jane Q., Mori, Hidetoshi, Cardiff, Robert D., Trott, Josephine F., Hovey, Russell C., Hubbard, Neil E., Engelberg, Jesse A., Tepper, Clifford G., Willis, Brandon J., Khan, Imran H., Ravindran, Resmi K., Chan, Szeman R., Schreiber, Robert D., Borowsky, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468083/
https://www.ncbi.nlm.nih.gov/pubmed/26075897
http://dx.doi.org/10.1371/journal.pone.0129895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468083/
https://www.ncbi.nlm.nih.gov/pubmed/26075897
http://dx.doi.org/10.1371/journal.pone.0129895

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