Systemic LPS Translocation Activates Cross-Presenting Dendritic Cells but Is Dispensable for the Breakdown of CD8(+) T Cell Peripheral Tolerance in Irradiated Mice

Lymphodepletion is currently used to enhance the efficacy of cytotoxic T lymphocyte adoptive transfer immunotherapy against cancer. This beneficial effect of conditioning regimens is due, at least in part, to promoting the breakdown of peripheral CD8(+) T cell tolerance. Lymphodepletion by total bod...

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Detalles Bibliográficos
Autores principales: Espinosa-Carrasco, Gabriel, Villard, Marine, Le Saout, Cecile, Louis-Plence, Pascale, Vicente, Rita, Hernandez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468093/
https://www.ncbi.nlm.nih.gov/pubmed/26075613
http://dx.doi.org/10.1371/journal.pone.0130041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468093/
https://www.ncbi.nlm.nih.gov/pubmed/26075613
http://dx.doi.org/10.1371/journal.pone.0130041

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