Computational Design of the β-Sheet Surface of a Red Fluorescent Protein Allows Control of Protein Oligomerization

Computational design has been used with mixed success for the design of protein surfaces, with directed evolution heretofore providing better practical solutions than explicit design. Directed evolution, however, requires a tractable high-throughput screen because the random nature of mutation does...

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Detalles Bibliográficos
Autores principales: Wannier, Timothy M., Moore, Matthew M., Mou, Yun, Mayo, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468108/
https://www.ncbi.nlm.nih.gov/pubmed/26075618
http://dx.doi.org/10.1371/journal.pone.0130582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468108/
https://www.ncbi.nlm.nih.gov/pubmed/26075618
http://dx.doi.org/10.1371/journal.pone.0130582

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