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Dopaminergic Neurons Respond to Iron-Induced Oxidative Stress by Modulating Lipid Acylation and Deacylation Cycles

Metal-imbalance has been reported as a contributor factor for the degeneration of dopaminergic neurons in Parkinson Disease (PD). Specifically, iron (Fe)-overload and copper (Cu) mis-compartmentalization have been reported to be involved in the injury of dopaminergic neurons in this pathology. The a...

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Detalles Bibliográficos
Autores principales: Sánchez Campos, Sofía, Rodríguez Diez, Guadalupe, Oresti, Gerardo Martín, Salvador, Gabriela Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468124/
https://www.ncbi.nlm.nih.gov/pubmed/26076361
http://dx.doi.org/10.1371/journal.pone.0130726