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The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity

Glucagon regulates glucose homeostasis by controlling glycogenolysis and gluconeogenesis in the liver. Exaggerated and dysregulated glucagon secretion can exacerbate hyperglycemia contributing to type 2 diabetes (T2D). Thus, it is important to understand how glucagon receptor (GCGR) activity and sig...

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Detalles Bibliográficos
Autores principales: Han, Junfeng, Zhang, Ming, Froese, Sean, Dai, Feihan F., Robitaille, Mélanie, Bhattacharjee, Alpana, Huang, Xinyi, Jia, Weiping, Angers, Stéphane, Wheeler, Michael B., Wei, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468146/
https://www.ncbi.nlm.nih.gov/pubmed/26075596
http://dx.doi.org/10.1371/journal.pone.0129226