Loss of Foxm1 Results in Reduced Somatotrope Cell Number during Mouse Embryogenesis

FOXM1, a member of the forkhead box transcription factor family, plays a key role in cell cycling progression by regulating the expression of critical G1/S and G2/M phase transition genes. In vivo studies reveal that Foxm1 null mice have a 91% lethality rate at e18.5 due to significant cardiovascula...

Descripción completa

Detalles Bibliográficos
Autores principales: Calderon, Michael J., Ploegman, Adam G., Bailey, Brock, Jung, Deborah O., Navratil, Amy M., Ellsworth, Buffy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468165/
https://www.ncbi.nlm.nih.gov/pubmed/26075743
http://dx.doi.org/10.1371/journal.pone.0128942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468165/
https://www.ncbi.nlm.nih.gov/pubmed/26075743
http://dx.doi.org/10.1371/journal.pone.0128942

Ejemplares similares