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Loss of Foxm1 Results in Reduced Somatotrope Cell Number during Mouse Embryogenesis
FOXM1, a member of the forkhead box transcription factor family, plays a key role in cell cycling progression by regulating the expression of critical G1/S and G2/M phase transition genes. In vivo studies reveal that Foxm1 null mice have a 91% lethality rate at e18.5 due to significant cardiovascula...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468165/ https://www.ncbi.nlm.nih.gov/pubmed/26075743 http://dx.doi.org/10.1371/journal.pone.0128942 |