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Intra-Arterial Transplantation of Allogeneic Mesenchymal Stem Cells Mounts Neuroprotective Effects in a Transient Ischemic Stroke Model in Rats: Analyses of Therapeutic Time Window and Its Mechanisms

OBJECTIVE: Intra-arterial stem cell transplantation exerts neuroprotective effects for ischemic stroke. However, the optimal therapeutic time window and mechanisms have not been completely understood. In this study, we investigated the relationship between the timing of intra-arterial transplantatio...

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Detalles Bibliográficos
Autores principales: Toyoshima, Atsuhiko, Yasuhara, Takao, Kameda, Masahiro, Morimoto, Jun, Takeuchi, Hayato, Wang, Feifei, Sasaki, Tatsuya, Sasada, Susumu, Shinko, Aiko, Wakamori, Takaaki, Okazaki, Mihoko, Kondo, Akihiko, Agari, Takashi, Borlongan, Cesario V., Date, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468176/
https://www.ncbi.nlm.nih.gov/pubmed/26075717
http://dx.doi.org/10.1371/journal.pone.0127302