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Pten Regulates Epithelial Cytodifferentiation during Prostate Development

Gene expression and functional studies have indicated that the molecular programmes involved in prostate development are also active in prostate cancer. PTEN has been implicated in human prostate cancer and is frequently mutated in this disease. Here, using the Nkx3.1:Cre mouse strain and a genetic...

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Detalles Bibliográficos
Autores principales: Lokody, Isabel B., Francis, Jeffrey C., Gardiner, Jennifer R., Erler, Janine T., Swain, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468205/
https://www.ncbi.nlm.nih.gov/pubmed/26076167
http://dx.doi.org/10.1371/journal.pone.0129470