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Sleep-Wake Cycle Dysfunction in the TgCRND8 Mouse Model of Alzheimer’s Disease: From Early to Advanced Pathological Stages

In addition to cognitive decline, individuals affected by Alzheimer’s disease (AD) can experience important neuropsychiatric symptoms including sleep disturbances. We characterized the sleep-wake cycle in the TgCRND8 mouse model of AD, which overexpresses a mutant human form of amyloid precursor pro...

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Detalles Bibliográficos
Autores principales: Colby-Milley, Jessica, Cavanagh, Chelsea, Jego, Sonia, Breitner, John C. S., Quirion, Rémi, Adamantidis, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468206/
https://www.ncbi.nlm.nih.gov/pubmed/26076358
http://dx.doi.org/10.1371/journal.pone.0130177