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Sleep-Wake Cycle Dysfunction in the TgCRND8 Mouse Model of Alzheimer’s Disease: From Early to Advanced Pathological Stages
In addition to cognitive decline, individuals affected by Alzheimer’s disease (AD) can experience important neuropsychiatric symptoms including sleep disturbances. We characterized the sleep-wake cycle in the TgCRND8 mouse model of AD, which overexpresses a mutant human form of amyloid precursor pro...
Autores principales: | Colby-Milley, Jessica, Cavanagh, Chelsea, Jego, Sonia, Breitner, John C. S., Quirion, Rémi, Adamantidis, Antoine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468206/ https://www.ncbi.nlm.nih.gov/pubmed/26076358 http://dx.doi.org/10.1371/journal.pone.0130177 |
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