Synoviocyte Derived-Extracellular Matrix Enhances Human Articular Chondrocyte Proliferation and Maintains Re-Differentiation Capacity at Both Low and Atmospheric Oxygen Tensions

BACKGROUND: Current tissue engineering methods are insufficient for total joint resurfacing, and chondrocytes undergo de-differentiation when expanded on tissue culture plastic. De-differentiated chondrocytes show poor re-differentiation in culture, giving reduced glycosaminoglycan (GAG) and collage...

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Detalles Bibliográficos
Autores principales: Kean, Thomas J., Dennis, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468209/
https://www.ncbi.nlm.nih.gov/pubmed/26075742
http://dx.doi.org/10.1371/journal.pone.0129961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468209/
https://www.ncbi.nlm.nih.gov/pubmed/26075742
http://dx.doi.org/10.1371/journal.pone.0129961

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