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Requirement of ATR for maintenance of intestinal stem cells in aging Drosophila

The stem cell genomic stability forms the basis for robust tissue homeostasis, particularly in high-turnover tissues. For the genomic stability, DNA damage response (DDR) is essential. This study was focused on the role of two major DDR-related factors, ataxia telangiectasia-mutated (ATM) and ATM- a...

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Detalles Bibliográficos
Autores principales: Park, Joung-Sun, Na, Hyun-Jin, Pyo, Jung-Hoon, Jeon, Ho-Jun, Kim, Young-Shin, Yoo, Mi-Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468312/
https://www.ncbi.nlm.nih.gov/pubmed/26000719