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AID/APOBEC deaminases and cancer

Mutations are the basis for evolution and the development of genetic diseases. Especially in cancer, somatic mutations in oncogenes and tumor suppressor genes alongside the occurrence of passenger mutations have been observed by recent deep-sequencing approaches. While mutations have long been consi...

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Detalles Bibliográficos
Autores principales: Rebhandl, Stefan, Huemer, Michael, Greil, Richard, Geisberger, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468319/
https://www.ncbi.nlm.nih.gov/pubmed/26097867