Rapid and efficient transfer of the T cell aging marker CD57 from glioblastoma stem cells to CAR T cells

Adoptive transfer of T cells expressing chimeric antigen receptors (CARs) holds great promise for cancer treatment. We recently developed CAR T cells targeting the prototypic cancer stem cell marker AC133 and showed that these CAR T cells killed AC133+ glioblastoma stem cells (GBM-SCs) in vitro and...

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Detalles Bibliográficos
Autores principales: Zhu, Xuekai, Niedermann, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468333/
https://www.ncbi.nlm.nih.gov/pubmed/26097880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468333/
https://www.ncbi.nlm.nih.gov/pubmed/26097880

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