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Uncovering potential downstream targets of oncogenic GRPR overexpression in prostate carcinomas harboring ETS rearrangements

Gastrin-releasing peptide receptor (GRPR) is known to be overexpressed in several human malignancies, including prostate cancer, and has been implicated in multiple important neoplastic signaling pathways. We recently have shown that GRPR is an ERG and ETV1 target gene in prostate cancer, using a ge...

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Detalles Bibliográficos
Autores principales: Santos, Joana, Mesquita, Diana, Barros-Silva, João D., Jerónimo, Carmen, Henrique, Rui, Morais, António, Paulo, Paula, Teixeira, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468336/
https://www.ncbi.nlm.nih.gov/pubmed/26097883