A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells

Pharmacologic inhibition of DNA repair may increase the efficacy of many cytotoxic cancer agents. Inhibitors of DNA repair enzymes including APE1, ATM, ATR, DNA-PK and PARP have been developed and the PARP inhibitor olaparib is the first-in-class approved in Europe and the USA for the treatment of a...

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Detalles Bibliográficos
Autores principales: Bakkenist, Christopher J., Czambel, R. Kenneth, Hershberger, Pamela A., Tawbi, Hussein, Beumer, Jan H., Schmitz, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468340/
https://www.ncbi.nlm.nih.gov/pubmed/26097887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468340/
https://www.ncbi.nlm.nih.gov/pubmed/26097887

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