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Limits on information transduction through amplitude and frequency regulation of transcription factor activity
Signaling pathways often transmit multiple signals through a single shared transcription factor (TF) and encode signal information by differentially regulating TF dynamics. However, signal information will be lost unless it can be reliably decoded by downstream genes. To understand the limits on dyn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468373/ https://www.ncbi.nlm.nih.gov/pubmed/25985085 http://dx.doi.org/10.7554/eLife.06559 |