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Can insulin signaling pathways be targeted to transport Aβ out of the brain?

Although the causal role of Amyloid-β (Aβ) in Alzheimer’s disease (AD) is unclear, it is still reasonable to expect that lowering concentrations of Aβ in the brain may decrease the risk of developing the neurocognitive symptoms of the disease. Brain capillary endothelial cells forming the blood-brai...

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Detalles Bibliográficos
Autores principales: Vandal, Milene, Bourassa, Philippe, Calon, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468380/
https://www.ncbi.nlm.nih.gov/pubmed/26136681
http://dx.doi.org/10.3389/fnagi.2015.00114