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CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma

Osteosarcoma is the most common primary bone malignancy in children and adolescents. Herein, we investigated the role of cluster of differentiation 44 (CD44), a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion, and migration in osteosarcoma. We constructed a human osteosar...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Feng, Yong, Shen, Jacson K., Lin, Min, Choy, Edwin, Cote, Gregory M., Harmon, David C., Mankin, Henry J., Hornicek, Francis J., Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468826/
https://www.ncbi.nlm.nih.gov/pubmed/26079799
http://dx.doi.org/10.1038/srep11365