Phasing of single DNA molecules by massively parallel barcoding

High-throughput sequencing platforms mainly produce short-read data, resulting in a loss of phasing information for many of the genetic variants analysed. For certain applications, it is vital to know which variant alleles are connected to each individual DNA molecule. Here we demonstrate a method f...

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Detalles Bibliográficos
Autores principales: Borgström, Erik, Redin, David, Lundin, Sverker, Berglund, Emelie, Andersson, Anders F., Ahmadian, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468844/
https://www.ncbi.nlm.nih.gov/pubmed/26055759
http://dx.doi.org/10.1038/ncomms8173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468844/
https://www.ncbi.nlm.nih.gov/pubmed/26055759
http://dx.doi.org/10.1038/ncomms8173

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