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Phasing of single DNA molecules by massively parallel barcoding
High-throughput sequencing platforms mainly produce short-read data, resulting in a loss of phasing information for many of the genetic variants analysed. For certain applications, it is vital to know which variant alleles are connected to each individual DNA molecule. Here we demonstrate a method f...
Autores principales: | Borgström, Erik, Redin, David, Lundin, Sverker, Berglund, Emelie, Andersson, Anders F., Ahmadian, Afshin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468844/ https://www.ncbi.nlm.nih.gov/pubmed/26055759 http://dx.doi.org/10.1038/ncomms8173 |
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