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Total synthesis of tetraacylated phosphatidylinositol hexamannoside and evaluation of its immunomodulatory activity

Tuberculosis, aggravated by drug-resistant strains and HIV co-infection of the causative agent Mycobacterium tuberculosis, is a global problem that affects millions of people. With essential immunoregulatory roles, phosphatidylinositol mannosides are among the cell-envelope components critical to th...

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Detalles Bibliográficos
Autores principales: Patil, Pratap S., Cheng, Ting-Jen Rachel, Zulueta, Medel Manuel L., Yang, Shih-Ting, Lico, Larry S., Hung, Shang-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468851/
https://www.ncbi.nlm.nih.gov/pubmed/26037164
http://dx.doi.org/10.1038/ncomms8239