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Disruption of Slc4a10 augments neuronal excitability and modulates synaptic short-term plasticity

Slc4a10 is a Na(+)-coupled Cl(−)-HCO(3)(−) exchanger, which is expressed in principal and inhibitory neurons as well as in choroid plexus epithelial cells of the brain. Slc4a10 knockout (KO) mice have collapsed brain ventricles and display an increased seizure threshold, while heterozygous deletions...

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Detalles Bibliográficos
Autores principales: Sinning, Anne, Liebmann, Lutz, Hübner, Christian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468864/
https://www.ncbi.nlm.nih.gov/pubmed/26136660
http://dx.doi.org/10.3389/fncel.2015.00223