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Engineering of lipid prodrug-based, hyaluronic acid-decorated nanostructured lipid carriers platform for 5-fluorouracil and cisplatin combination gastric cancer therapy

PURPOSE: The first-line chemotherapy treatment protocol for gastric cancer is combination chemotherapy of 5-fluorouracil (5-FU) and cisplatin (CDDP). The aim of this study was to engineer prodrug-based nanostructured lipid carriers (NLC) platform for codelivery of 5-FU and CDDP to enhance therapy an...

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Detalles Bibliográficos
Autores principales: Qu, Chun-Ying, Zhou, Min, Chen, Ying-wei, Chen, Mei-mei, Shen, Feng, Xu, Lei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468988/
https://www.ncbi.nlm.nih.gov/pubmed/26089667
http://dx.doi.org/10.2147/IJN.S83211