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RZZ and Mad1 dynamics in Drosophila mitosis

The presence or absence of Mad1 at kinetochores is a major determinant of spindle assembly checkpoint (SAC) activity, the surveillance mechanism that delays anaphase onset if one or more kinetochores remain unattached to spindle fibers. Among the factors regulating the levels of Mad1 at kinetochores...

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Detalles Bibliográficos
Autores principales: Défachelles, Lénaïg, Raich, Natacha, Terracol, Régine, Baudin, Xavier, Williams, Byron, Goldberg, Michael, Karess, Roger E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469085/
https://www.ncbi.nlm.nih.gov/pubmed/25772408
http://dx.doi.org/10.1007/s10577-015-9472-x