Regulation of DCIS to invasive breast cancer progression by Singleminded-2s (SIM2s)

Singleminded-2s (SIM2s) is a member of the bHLH/PAS family of transcription factors and a key regulator of mammary epithelial cell differentiation. SIM2s is highly expressed in mammary epithelial cells and down regulated in human breast cancer. Loss of Sim2s causes aberrant mouse mammary ductal deve...

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Detalles Bibliográficos
Autores principales: Scribner, Kelly C., Behbod, Fariba, Porter, Weston W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469191/
https://www.ncbi.nlm.nih.gov/pubmed/22777354
http://dx.doi.org/10.1038/onc.2012.286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469191/
https://www.ncbi.nlm.nih.gov/pubmed/22777354
http://dx.doi.org/10.1038/onc.2012.286

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