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Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities

Synaptic failure is an immediate cause of cognitive decline and memory dysfunction in Alzheimer’s disease. Dendritic spines are specialized structures on neuronal processes, on which excitatory synaptic contacts take place and the loss of dendritic spines directly correlates with the loss of synapti...

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Detalles Bibliográficos
Autores principales: Dorostkar, Mario M., Zou, Chengyu, Blazquez-Llorca, Lidia, Herms, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469300/
https://www.ncbi.nlm.nih.gov/pubmed/26063233
http://dx.doi.org/10.1007/s00401-015-1449-5