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Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities
Synaptic failure is an immediate cause of cognitive decline and memory dysfunction in Alzheimer’s disease. Dendritic spines are specialized structures on neuronal processes, on which excitatory synaptic contacts take place and the loss of dendritic spines directly correlates with the loss of synapti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469300/ https://www.ncbi.nlm.nih.gov/pubmed/26063233 http://dx.doi.org/10.1007/s00401-015-1449-5 |