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Immune modulating effects of cyclophosphamide and treatment with tumor lysate/CpG synergize to eliminate murine neuroblastoma

BACKGROUND: Neuroblastoma is a pediatric cancer of neural crest origin. Despite aggressive treatment, mortality remains at 40 % for patients with high-risk disseminated disease, underscoring the need to test new combinations of therapies. In murine tumor models, our laboratory previously showed that...

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Detalles Bibliográficos
Autores principales: Gershan, Jill A., Barr, Kristen M., Weber, James J., Jing, Weiqing, Johnson, Bryon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469315/
https://www.ncbi.nlm.nih.gov/pubmed/26082836
http://dx.doi.org/10.1186/s40425-015-0071-3