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A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain
Cancer pain is a debilitating disorder and a primary determinant of the poor quality of life. Here, we report a non-vascular role for ligands of the Vascular Endothelial Growth Factor (VEGF) family in cancer pain. Tumor-derived VEGF-A, PLGF-2, and VEGF-B augment pain sensitivity through selective ac...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469373/ https://www.ncbi.nlm.nih.gov/pubmed/26058077 http://dx.doi.org/10.1016/j.ccell.2015.04.017 |