A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain

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Cancer pain is a debilitating disorder and a primary determinant of the poor quality of life. Here, we report a non-vascular role for ligands of the Vascular Endothelial Growth Factor (VEGF) family in cancer pain. Tumor-derived VEGF-A, PLGF-2, and VEGF-B augment pain sensitivity through selective ac...

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Detalles Bibliográficos
Autores principales: Selvaraj, Deepitha, Gangadharan, Vijayan, Michalski, Christoph W., Kurejova, Martina, Stösser, Sebastian, Srivastava, Kshitij, Schweizerhof, Matthias, Waltenberger, Johannes, Ferrara, Napoleone, Heppenstall, Paul, Shibuya, Masabumi, Augustin, Hellmut G., Kuner, Rohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469373/
https://www.ncbi.nlm.nih.gov/pubmed/26058077
http://dx.doi.org/10.1016/j.ccell.2015.04.017

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