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Rewriting the blueprint of life by synthetic genomics and genome engineering

Advances in DNA synthesis and assembly methods over the past decade have made it possible to construct genome-size fragments from oligonucleotides. Early work focused on synthesis of small viral genomes, followed by hierarchical synthesis of wild-type bacterial genomes and subsequently on transplant...

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Detalles Bibliográficos
Autores principales: Annaluru, Narayana, Ramalingam, Sivaprakash, Chandrasegaran, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469412/
https://www.ncbi.nlm.nih.gov/pubmed/26076868
http://dx.doi.org/10.1186/s13059-015-0689-y