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Rewriting the blueprint of life by synthetic genomics and genome engineering
Advances in DNA synthesis and assembly methods over the past decade have made it possible to construct genome-size fragments from oligonucleotides. Early work focused on synthesis of small viral genomes, followed by hierarchical synthesis of wild-type bacterial genomes and subsequently on transplant...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469412/ https://www.ncbi.nlm.nih.gov/pubmed/26076868 http://dx.doi.org/10.1186/s13059-015-0689-y |